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Briefly, the model states that the generation of an action potential is determined by two ions: Na and K .

An action potential can be divided into several sequential phases: threshold, rising phase, falling phase, undershoot phase, and recovery.

These vesicles are pooled together in terminal boutons of the presynaptic neuron.

When there is a change in voltage in the terminal bouton, voltage-gated calcium channels embedded in the membranes of these boutons become activated.

Thus, the fundamental difference between a neuron and a nonneuronal cell is a matter of degree.

The Hodgkin–Huxley model of an action potential in the squid giant axon has been the basis for much of the current understanding of the ionic bases of action potentials.

In the human brain alone, there are over eighty billion neurons.

There are two families of receptors: ionotropic and metabotropic receptors.

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If more of the same type of postsynaptic receptors are activated, then more Na will enter the postsynaptic membrane and depolarize cell.

Metabotropic receptors on the other hand activate second messenger cascade systems that result in the opening of ion channel located some place else on the same postsynaptic membrane.

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  1. Thanks for listening.” Implicit in your question seems to be a fear that by acknowledging your ex-husband’s abuse, you’ll either be flagged as someone who violates professional and social etiquette, or be thought of as a “downer.” I don’t think that’s the case.

  2. Due to the potential for emotional intimacy between those who have engaged in phone sex, it is a matter of some debate whether phone sex is to be considered infidelity when involving a person outside of a committed personal relationship.